Violacein Treatment Modulates Acute and Chronic Inflammation through the Suppression of Cytokine Production and Induction of Regulatory T Cells: e0125409

• Published in: PloS one Vol. 10; no. 5
• Main Authors: Verinaud, Liana, Lopes, Stefanie CostaPinto, Prado, Isabel CristinaNaranjo, Zanucoli, Fabio, Costa, Thiago Alvesda, Gangi, Rosaria Di, Issayama, Luidy Kazuo, Carvalho, Ana Carolina, Bonfanti, Amanda Pires, Niederauer, Guilherme Francio
• Format: Journal Article
• Language: English
• Published: 01.05.2015
• Subjects: Chromobacterium violaceum

Inflammation is a necessary process to control infection. However, exacerbated inflammation, acute or chronic, promotes deleterious effects in the organism. Violacein (viola), a quorum sensing metabolite from the Gram-negative bacterium Chromobacterium violaceum, has been shown to protect mice from...