Synthetic utility of KabachnikaFields reaction: a convenient one-pot three-component synthesis of N-phenyl isoquinolone-1-phosphonates
A convenient, one-pot three-component synthesis of novel N-phenyl isoquinolone-1-phosphonates (4aa4g) using the KabachnikaFields reaction, starting from ethyl 2-(2-formyl-4,5-dimethoxyphenyl) acetate (1) and anilines (2aa2g) is described. The aldehyde (1) on reaction with substituted anilines (2aa2g...
Saved in:
| Published in | Tetrahedron letters Vol. 53; no. 51; pp. 6940 - 6942 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
19.12.2012
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | A convenient, one-pot three-component synthesis of novel N-phenyl isoquinolone-1-phosphonates (4aa4g) using the KabachnikaFields reaction, starting from ethyl 2-(2-formyl-4,5-dimethoxyphenyl) acetate (1) and anilines (2aa2g) is described. The aldehyde (1) on reaction with substituted anilines (2aa2g) and triethyl phosphite in acetonitrile using trifluroacetic acid as catalyst provides N-phenyl isoquinolone-1-phosphonates (4aa4g) in good yields. |
|---|---|
| AbstractList | A convenient, one-pot three-component synthesis of novel N-phenyl isoquinolone-1-phosphonates (4aa4g) using the KabachnikaFields reaction, starting from ethyl 2-(2-formyl-4,5-dimethoxyphenyl) acetate (1) and anilines (2aa2g) is described. The aldehyde (1) on reaction with substituted anilines (2aa2g) and triethyl phosphite in acetonitrile using trifluroacetic acid as catalyst provides N-phenyl isoquinolone-1-phosphonates (4aa4g) in good yields. |
| Author | Patil, Nilesh L Mali, Raghao S Borse, Amulrao U Patil, Mahesh N |
| Author_xml | – sequence: 1 givenname: Amulrao surname: Borse middlename: U fullname: Borse, Amulrao U – sequence: 2 givenname: Nilesh surname: Patil middlename: L fullname: Patil, Nilesh L – sequence: 3 givenname: Mahesh surname: Patil middlename: N fullname: Patil, Mahesh N – sequence: 4 givenname: Raghao surname: Mali middlename: S fullname: Mali, Raghao S |
| BookMark | eNqVjc9Kw0AQxvdQoa32DTzs0UvibBNi41UsguCl3su6TsnU7WzMTIS8gM_tVnwBBz4Gfnx_lmbGidGYawelA9fcHktFjajlGtw6oxIqmJkFQA1FDVU7N0uRI-RrNrAw37uJtUOlYEelSDrZdLDP_s2HjunDbwnju9gBfVBKfG-9DYm_kAlZbZ4u-qRWuwGxCOnUZ5K5_JYKybnspeg75ClakvQ5Eqd4jrlMk2SxV5Qrc3HwUXD19y_Nzfbx9eGp6IecQdH9iSRgjJ4xjbJ3d3XdtFVbb6p_WH8AnJVgpw |
| ContentType | Journal Article |
| DBID | 7SR 7U5 8BQ 8FD JG9 L7M |
| DOI | 10.1016/j.tetlet.2012.10.030 |
| DatabaseName | Engineered Materials Abstracts Solid State and Superconductivity Abstracts METADEX Technology Research Database Materials Research Database Advanced Technologies Database with Aerospace |
| DatabaseTitle | Materials Research Database Engineered Materials Abstracts Technology Research Database Solid State and Superconductivity Abstracts Advanced Technologies Database with Aerospace METADEX |
| DatabaseTitleList | Materials Research Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry |
| EndPage | 6942 |
| GroupedDBID | --- --K --M -ET -~X .~1 0R~ 123 1B1 1RT 1~. 1~5 4.4 457 4G. 53G 5VS 7-5 71M 7SR 7U5 85S 8BQ 8FD 8P~ 9JM 9JN AABNK AACTN AAEDT AAEDW AAHBH AAIKJ AAKOC AALRI AAOAW AAQFI AARLI AAXUO ABFNM ABFRF ABGSF ABJNI ABMAC ABPPZ ABUDA ABXDB ABZDS ACBEA ACDAQ ACGFS ACNCT ACNNM ACRLP ADBBV ADECG ADEZE ADMUD ADUVX AEBSH AEFWE AEHWI AEKER AENEX AFKWA AFTJW AFXIZ AFZHZ AGHFR AGUBO AGYEJ AHHHB AIEXJ AIKHN AITUG AJOXV AJSZI AKRWK ALCLG ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AXJTR BKOJK BLXMC CS3 DU5 EBS EFJIC EJD EO8 EO9 EP2 EP3 F5P FDB FIRID FLBIZ FNPLU FYGXN G-Q GBLVA HZ~ IH2 J1W JG9 K-O KOM L7M M2Z M41 MO0 N9A O-L O9- OAUVE OGGZJ OZT P-8 P-9 P2P PC. Q38 RIG RNS ROL RPZ SCC SDF SDG SDP SES SPC SPCBC SSK SSP SSU SSZ T5K TN5 TWZ WH7 XPP XSW YK3 YR2 ZMT ~02 ~G- ~KM |
| ID | FETCH-proquest_miscellaneous_17446939483 |
| ISSN | 0040-4039 |
| IngestDate | Fri Aug 16 04:31:15 EDT 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 51 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-proquest_miscellaneous_17446939483 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Feature-2 |
| PQID | 1744693948 |
| PQPubID | 23500 |
| ParticipantIDs | proquest_miscellaneous_1744693948 |
| PublicationCentury | 2000 |
| PublicationDate | 20121219 |
| PublicationDateYYYYMMDD | 2012-12-19 |
| PublicationDate_xml | – month: 12 year: 2012 text: 20121219 day: 19 |
| PublicationDecade | 2010 |
| PublicationTitle | Tetrahedron letters |
| PublicationYear | 2012 |
| SSID | ssj0000680 |
| Score | 4.169053 |
| Snippet | A convenient, one-pot three-component synthesis of novel N-phenyl isoquinolone-1-phosphonates (4aa4g) using the KabachnikaFields reaction, starting from ethyl... |
| SourceID | proquest |
| SourceType | Aggregation Database |
| StartPage | 6940 |
| SubjectTerms | Acetates Acetonitrile Aniline Catalysts Inorganic salts Synthesis (chemistry) Tetrahedrons Utilities |
| Title | Synthetic utility of KabachnikaFields reaction: a convenient one-pot three-component synthesis of N-phenyl isoquinolone-1-phosphonates |
| URI | https://search.proquest.com/docview/1744693948 |
| Volume | 53 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT8JAEN6gHvRifMZ31sSDCSmhDwrrzRiJUcRESsKNbOlWUGxNWw568Kh_25nulqIYRS9N2cK0zXzM7M58M0vIke3bPe7rXGPCFGm0SuM262l-zTA9r1LF3nfItmjaF23rslPpFArvE6ylUeKWei_f1pX8R6swBnrFKtk_aHYsFAbgHPQLR9AwHGfSces5gPkbtlyFmwwVueKKuxz7sj7wOrLTMC0gixdkXbOkmQ9SCkAgtKcQixkjITQkl8MIjMepWNWppKkhC-x5WBzE4EMGGIaHn-kwGsbIa8e56uQM1xEJ2C_hRQCrYVorlAfiw0hu43j6OBpGPCy28wRWImPRTTBScb_YmLpwDTLhwjhxdM1lXfctv-uDpNZk9EJPN1JRNlJZZKsMa1jZ0CizyLJ9sEKe6kcr7avNZHMn5avho_GtH5AhiftSIuDNkTKrGyUk8akc0Ke2282bbr3daHSd844zRxaMKqvgKr70qk-49Fo5o1_iw2Y1mClRcPoeU349naw4K2RZrTLoqYTMKimIYI0snmWb-62TtzF0qIIODX36FTo0g84J5TQHDlXAoV-AQ8fAQWEZcOgPwNkgx_Vz5-xCy16kCw-IuSQeiHAUd2Eha9nMZPDv3iTzAQjYIlQ3K64hdM6Y4Vue4dc8v2pxq2q6nNdEmW2Tw1_F7czwnV2ylGNpj8wn0Ujsw9wwcQ9SvX0ALa1zRw |
| link.rule.ids | 315,786,790,27957,27958 |
| linkProvider | Elsevier |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Synthetic+utility+of+KabachnikaFields+reaction%3A+a+convenient+one-pot+three-component+synthesis+of+N-phenyl+isoquinolone-1-phosphonates&rft.jtitle=Tetrahedron+letters&rft.au=Borse%2C+Amulrao+U&rft.au=Patil%2C+Nilesh+L&rft.au=Patil%2C+Mahesh+N&rft.au=Mali%2C+Raghao+S&rft.date=2012-12-19&rft.issn=0040-4039&rft.volume=53&rft.issue=51&rft.spage=6940&rft.epage=6942&rft_id=info:doi/10.1016%2Fj.tetlet.2012.10.030&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0040-4039&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0040-4039&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0040-4039&client=summon |