Translocation and Down-Regulation of Protein Kinase C- sub( alpha ), beta , and - sub( gamma ) Isoforms During Ischemia-Reperfusion in Rat Brain

• Published in: Journal of neurochemistry Vol. 72; no. 6; pp. 2556 - 2564
• Main Authors: Harada, Kazuki, Maekawa, Tsuyoshi, Shama, KMA, Yamashima, Tetsumori, Yoshida, Ken-ichi
• Format: Journal Article
• Language: English
• Published: 01.06.1999

We investigated the distribution of protein kinase C (PKC) isoforms in the subcellular fractions (P1, 1,000-g pellet; P2, 10,000-g pellet; P3, 100,000-g pellet; S, 100,000-g supernatant) of rat forebrain after ischemia or reperfusion by immunoblotting. PKC- sub( delta ) and - sub( epsilon ) isoforms...