Potent KCNQ2/3-Specific Channel Activator Suppresses In Vivo Epileptic Activity and Prevents the Development of Tinnitus

Voltage-gated Kv7 (KCNQ) channels are voltage-dependent potassium channels that are activated at resting membrane potentials and therefore provide a powerful brake on neuronal excitability. Genetic or experience-dependent reduction of KCNQ2/3 channel activity is linked with disorders that are charac...

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Bibliographic Details
Published inThe Journal of neuroscience Vol. 35; no. 23; pp. 8829 - 8842
Main Authors Kalappa, Bopanna I, Soh, Heun, Duignan, Kevin M, Furuya, Takeru, Edwards, Scott, Tzingounis, Anastasios V, Tzounopoulos, Thanos
Format Journal Article
LanguageEnglish
Published 10.06.2015
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