The Effect Of Hydroxyurea On The Phosphorylation Of Zidovudine And Lamivudine In Human Umbilical Vein Endothelial Cells

• Published in: In vitro cellular & developmental biology. Animal Vol. 39; no. 7; pp. 280 - 282
• Main Authors: Mcguire, T R, Hoie, E B, Manouilov, K K, Gwilt, P G
• Format: Journal Article
• Language: English
• Published: 01.07.2003

The purpose of this study was to characterize the activation of zidovudine (ZDV) and lamivudine (3TC) in human umbilical vein endothelial cells (HUVEC) with and without hydroxyurea (HU) pretreatment. HUVEC were pretreated with HU or control media for 24 h and then incubated for an additional 3 h wit...