Extracorporeal photopheresis performed on the CELLEX registered compared with the UVAR-XTS registered instrument is more efficient and better tolerated in children with steroid-refractory graft-versus-host disease

Extracorporeal photopheresis (ECP) is an effective therapy in children with refractory graft-versus-host disease (GVHD). The two most frequently used instruments are UVAR-XTS registered and CELLEX registered . We performed a retrospective chart review of ten patients who underwent ECP with both UVAR...

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Published inPediatric blood & cancer Vol. 62; no. 8; pp. 1485 - 1488
Main Authors Kapadia, Ekta, Wong, Edward, Perez-Albuerne, Evelio, Jacobsohn, David
Format Journal Article
LanguageEnglish
Published 01.08.2015
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Summary:Extracorporeal photopheresis (ECP) is an effective therapy in children with refractory graft-versus-host disease (GVHD). The two most frequently used instruments are UVAR-XTS registered and CELLEX registered . We performed a retrospective chart review of ten patients who underwent ECP with both UVAR-XTS registered and CELLEX registered instruments for steroid-refractory acute or chronic GVHD to compare instrument run times, percentages of cells treated, and complication rates. We found that compared to the UVAR-XTS registered instrument, use of the CELLEX registered instrument resulted in shorter run times, increased percentage of mononuclear cells treated, reduced incidence of line occlusions requiring TPA treatment, and decreased incidence of patient-related complications. Pediatr Blood Cancer 2015; 62:1485-1488.
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SourceType-Scholarly Journals-1
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ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.25487