Probing the Solution Structure of I Kappa B Kinase (IKK) Subunit gamma and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit beta by EPR Spectroscopy<inline-graphic xlink:href="sbox.jpg"/>

• Published in: The Journal of biological chemistry Vol. 290; no. 27; pp. 16539 - 16549
• Main Authors: Bagneris, Claire, Rogala, Kacper B, Baratchian, Mehdi, Zamfir, Vlad, Kunze, Micha BA, Dagless, Selina, Pirker, Katharina F, Collins, Mary K, Hall, Benjamin A, Barrett, Tracey E, Kay, Christopher WM
• Format: Journal Article
• Language: English
• Published: 04.05.2015
• Subjects: Herpesvirus; Kaposi's sarcoma-associated herpesvirus

Background: The I Kappa B kinase subunit gamma (IKK gamma ) is an essential modulator of the IKK signalosome whose solution structure is unsolved. Results: IKK gamma is a parallel coiled-coil comprising two registers accommodated by a twist. Conclusion: The response of IKK gamma to binding of signal...