Physical analysis of the region deleted in the t super(w18) allele of the mouse tcl-4 complementation group
We have generated a YAC contig of at least 3.3 Mb from the proximal region of In(17)4 of mouse chromosome 17. This region corresponds to DNA lost in the gastrulation mutant t super(w18), which belongs to the tcl-4 complementation group. Our most proximal and distal probes lie within the deletion-3.3...
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Published in | Genomics (San Diego, Calif.) Vol. 36; no. 1; pp. 39 - 46 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
01.08.1996
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Online Access | Get full text |
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Abstract | We have generated a YAC contig of at least 3.3 Mb from the proximal region of In(17)4 of mouse chromosome 17. This region corresponds to DNA lost in the gastrulation mutant t super(w18), which belongs to the tcl-4 complementation group. Our most proximal and distal probes lie within the deletion-3.3 Mb apart-indicating that we have not cloned the entire region. The deleted region is contained in a genetic interval of less than 1 cM, suggesting that some suppression of recombination must occur. |
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AbstractList | We have generated a YAC contig of at least 3.3 Mb from the proximal region of In(17)4 of mouse chromosome 17. This region corresponds to DNA lost in the gastrulation mutant t super(w18), which belongs to the tcl-4 complementation group. Our most proximal and distal probes lie within the deletion-3.3 Mb apart-indicating that we have not cloned the entire region. The deleted region is contained in a genetic interval of less than 1 cM, suggesting that some suppression of recombination must occur. |
Author | Barnard, R C Barclay, J Lehrach, H Crossley, PH Little, PFR King, T F Larin, Z |
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Title | Physical analysis of the region deleted in the t super(w18) allele of the mouse tcl-4 complementation group |
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