Intestinal Barrier Dysfunction Develops at the Onset of Experimental Autoimmune Encephalomyelitis, and Can Be Induced by Adoptive Transfer of Auto-Reactive T Cells: e106335

• Published in: PloS one Vol. 9; no. 9
• Main Authors: Nouri, Mehrnaz, Bredberg, Anders, Westrom, Bjorn, Lavasani, Shahram
• Format: Journal Article
• Language: English
• Published: 01.09.2014

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with a pathogenesis involving a dysfunctional blood-brain barrier and myelin-specific, autoreactive T cells. Although the commensal microbiota seems to affect its pathogenesis, regulation of the int...