B7-H1 signaling is integrated during CD8 super(+) T cell priming and restrains effector differentiation

• Published in: Cancer Immunology, Immunotherapy Vol. 63; no. 8; pp. 859 - 867
• Main Authors: Gibbons, Rachel M, Liu, Xin, Harrington, Susan M, Krco, Christopher J, Kwon, Eugene D, Dong, Haidong
• Format: Journal Article
• Language: English
• Published: 01.08.2014

A promising strategy in tumor immunotherapy is the use of activated dendritic cells as vehicles for tumor vaccines with the goal of activating anti-tumor T cell responses. Current formulations for dendritic cell-based immunotherapies have limited effects on patient survival, providing motivation for...