Receptor reserve for 5-hydroxytryptamine sub(1A)-mediated inhibition of serotonin synthesis: Possible relationship to anxiolytic properties of 5-hydroxytryptamine sub(1A) agonists

• Published in: Molecular pharmacology Vol. 37; no. 2; pp. 231 - 237
• Main Authors: Meller, E, Goldstein, M, Bohmaker, K
• Format: Journal Article
• Language: English
• Published: 01.01.1990

The irreversible receptor antagonist N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) was used to determine the relationship between receptor occupancy and response at central 5-hydroxytryptamine sub(1A) (5-HT sub(1A)) serotonin receptors mediating the inhibition of serotonin synthesis in rat c...