Role of Pathogenicity Determinant Protein C (PdpC) in Determining the Virulence of the Francisella tularensis Subspecies tularensis SCHU: e89075

• Published in: PloS one Vol. 9; no. 2
• Main Authors: Uda, Akihiko, Sekizuka, Tsuyoshi, Tanabayashi, Kiyoshi, Fujita, Osamu, Kuroda, Makoto, Hotta, Akitoyo, Sugiura, Naoko, Sharma, Neekun, Morikawa, Shigeru, Yamada, Akio
• Format: Journal Article
• Language: English
• Published: 01.02.2014
• Subjects: Francisella tularensis

Francisella tularensis subspecies tularensis, the etiological agent of tularemia, is highly pathogenic to humans and animals. However, the SCHU strain of F. tularensis SCHU P0 maintained by passaging in artificial media has been found to be attenuated. To better understand the molecular mechanisms b...