Teratogenicity of the Semliki Forest virus mutant ts 22 for the foetal mouse: Induction of skeletal and skin defects

• Published in: Journal of general virology Vol. 69; no. 11; pp. 2755 - 2762
• Main Authors: Mabruk, MJEMF, Flack, A M, Glasgow, G M, Smyth, JMB, Folan, J C, Bannigan, J G, O'Sullivan, MA, Sheahan, B J, Atkins, G J
• Format: Journal Article
• Language: English
• Published: 01.01.1988

The maximum proportion of skeletal and/or skin defects induced by the Semliki Forest virus (SFV) mutant ts 22 in the 17-day-old foetal mouse occurred following infection of the mother at day 10 of pregnancy. The skeletal defects were detected using a combination of Alcian blue staining for cartilage...