DUAL ENDOTHELIN RECEPTOR ANTAGONIST REDUCES SUBCELLULAR ORGANELLES DAMAGE IN CEREBRAL CORTEX NEURONS IN EXPERIMENTAL MODEL OF CARDIAC ARREST

• Published in: Acta neurobiologiae experimentalis Vol. 73; p. 28
• Main Authors: Ostrowski, R P, Januszewski, S, Kowalska, L, Kapuscinski, A, Frontczak-Baniewicz, M, Pucko, E B, Matyja, E
• Format: Journal Article
• Language: English
• Published: 01.01.2013

In the present study we investigated the effect of dual endothelin receptor (ETR) antagonist bosentan on postischemic structural abnormalities of subcellular organelles in neurons of cerebral cortex and on endothelin binding sites in the brain after 10 min of cardiac arrest in male Wistar rats. Afte...