Decreased brain intracellular pH measured by super(31)P-MRS in bipolar disorder: a confirmation in drug-free patients and correlation with white matter hyperintensity

• Published in: European archives of psychiatry and clinical neuroscience Vol. 248; no. 6; pp. 301 - 306
• Main Authors: Kato, T, Murashita, J, Kamiya, Atsushi, Shioiri, Toshiki, Kato, Nobumasa, Inubushi, Toshiro
• Format: Journal Article
• Language: English
• Published: 01.12.1998

The authors have previously reported decreased intracellular pH (pHi) in the frontal lobes in euthymic bipolar patients treated with lithium using super(31)P-MRS. White matter hyperintensity (WMHI) is frequently seen in bipolar disorder. To examine a possible effect of lithium on pHi and the relatio...