miR-126 and miR-126 super() repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis

• Published in: Nature cell biology Vol. 15; no. 3; pp. 284 - 294
• Main Authors: Zhang, Yun, Yang, Pengyuan, Sun, Tao, Li, Dong, Xu, Xin, Rui, Yaocheng, Li, Chaoran, Chong, Mengyang, Ibrahim, Toni, Mercatali, Laura, Amadori, Dino, Lu, Xincheng, Xie, Dong, Li, Qi-Jing, Wang, Xiao-Fan
• Format: Journal Article
• Language: English
• Published: 01.03.2013
• Subjects: Angiogenesis

The tumour stroma is an active participant during cancer progression. Stromal cells promote tumour progression and metastasis through multiple mechanisms including enhancing tumour invasiveness and angiogenesis, and suppressing immune surveillance. We report here that miR-126/miR-126 super(*), a mic...