Gating of alpha sub(3) beta sub(4) neuronal nicotinic receptor can be controlled by the loop M2-M3 of both alpha sub(3) and beta sub(4) subunits

• Published in: Pflügers Archiv Vol. 439; no. 1-2; pp. 86 - 92
• Main Authors: Rovira, J C, Vicente-Agullo, F, Campos-Caro, A, Criado, M, Sala, F, Sala, S, Ballesta, J J
• Format: Journal Article
• Language: English
• Published: 01.12.1999
• Subjects: Acetylcholine receptors (nicotinic); Xenopus

Previous studies have shown that the gating mechanism of alpha sub(3) beta sub(4) neuronal nicotinic receptors is affected by a residue in the middle of the M2-M3 loop of the beta sub(4) subunit. We have extended the study of the same location to the alpha sub(3) subunit. Bovine alpha sub(3) beta su...