Regulation of Neurod1 Contributes to the Lineage Potential of Neurogenin3+ Endocrine Precursor Cells in the Pancreas. e1003278

• Published in: PLoS genetics Vol. 9; no. 2
• Main Authors: Mastracci, Teresa L, Anderson, Keith R, Papizan, James B, Sussel, Lori
• Format: Journal Article
• Language: English
• Published: 01.02.2013
• Subjects: Beta cells; Beta2 protein; Cell fate; Cell lineage; Differentiation; Nkx2.2 protein; Pancreas; Stem cells; Transcription factors

During pancreatic development, transcription factor cascades gradually commit precursor populations to the different endocrine cell fate pathways. Although mutational analyses have defined the functions of many individual pancreatic transcription factors, the integrative transcription factor network...