Bitterness Evaluation of H(1)-Receptor Antagonists Using a Taste Sensor

• Published in: Sensors and materials Vol. 23; no. 8; pp. 483 - 492
• Main Authors: Ito, Masanori, Yoshida, Miyako, Kobayashi, Yoshikazu, Hiraoka, Masamitsu, Ikezaki, Hidekazu, Uchida, Takahiro
• Format: Journal Article
• Language: English
• Published: 01.01.2011
• Subjects: Adsorption; Bitterness; Hydrophobicity; Membranes; Principal component analysis; Sensors; Surface chemistry; Taste

The objective of this study was to evaluate an improved bitterness sensor, which, it is postulated, will allow a more precise and sensitive prediction of the bitterness of active pharmaceutical substances. The bitterness sensor, BTO, has a membrane surface with improved and optimized hydrophobicity,...