Cold tolerance, cold-induced hyperphagia, and nonshivering thermogenesis are normal in [alpha]^sub 1^-AMPK-/- mice

• Published in: American journal of physiology. Regulatory, integrative and comparative physiology Vol. 301; no. 2; p. R473
• Main Authors: Bauwens, Jake D, Schmuck, Eric G, Lindholm, Christopher R, Ertel, Rebecca L, Mulligan, Jacob D, Hovis, Ian, Viollet, Benoit, Saupe, Kurt W
• Format: Journal Article
• Language: English
• Published: Bethesda American Physiological Society 01.08.2011
• Subjects: Genes; Kinases; Metabolism; Rodents; Tissues

Recent studies indicate that a substantial amount of metabolically active brown adipose tissue (BAT) exists in adult humans. Given the unique ability of BAT to convert calories to heat, there is intense interest in understanding the regulation of BAT metabolism in hopes that its manipulation might b...