Effects of RNA interference-induced tryptase down-regulation in P815 cells on IL-6 and TNF-[alpha] release of endothelial cells

• Published in: Journal of Zhejiang University. B. Science Vol. 9; no. 8; p. 656
• Main Authors: Jiang, Yi-feng, Zhao, Feng-di, Li, Xiao-bo, Ning, Yan-xia, Zhi, Xiu-ling, Qian, Rui-zhe, Yin, Lian-hua
• Format: Journal Article
• Language: English
• Published: Hangzhou Springer Nature B.V 01.08.2008
• Subjects: Cells; Proteins

To explore the effects of down-regulated tryptase expression in mast cells on the synthesis and release of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) of vascular endothelial cells. Tryptase-siRNA (small-interfering RNA) vector was constructed to inhibit tryptase expression in P815...