71-OR: Rates of Remission and Metabolic Responses in Data-Driven High-Risk Prediabetes Clusters

• Published in: Diabetes (New York, N.Y.) Vol. 73; p. 1
• Main Authors: Katzenstein, Sarah, Sandforth, Arvid, Faiao, Vitoria Minelli, Sandforth, Leontine, Schick, Fritz, Machann, Jürgen, Peter, Andreas, Seissler, Jochen, Perakakis, Nikolaos, Schürmann, Annette, Pfeiffer, Andreas F, Kabisch, Stefan, Blüher, Matthias, Szendroedi, Julia, Solimena, Michele, Bornstein, Stefan R, Fritsche, Andreas, Wagner, Robert, Roden, Michael, Stefan, Norbert, Von Schwartzenberg, Reiner Jumpertz, Birkenfeld, Andreas L
• Format: Journal Article
• Language: English
• Published: New York American Diabetes Association 01.06.2024
• Subjects: Adipose tissue; Body fat; Diabetes mellitus (non-insulin dependent); Insulin secretion; Liver; Metabolic response; Phenotyping; Remission; Remission (Medicine); Weight

We have previously shown that weight loss-induced remission of prediabetes is mediated by improved insulin sensitivity (IS) and characterized by reduced visceral adipose tissue mass (VAT). Remission markedly reduces the risk for type 2 diabetes. We hypothesized that patients from specific high-risk...