A single-cell atlas of transcribed cis-regulatory elements in the human genome

• Published in: bioRxiv
• Main Authors: Moody, Jonathan, Kouno, Tsukasa, Kojima, Miki, Koya, Ikuko, Leon, Julio, Suzuki, Akari, Hasegawa, Akira, Akiyama, Taishin, Akiyama, Nobuko, Amagai, Masayuki, Jen-Chien, Chang, Fukushima-Nomura, Ayano, Handa, Mika, Hino, Kazunori, Hino, Mizuki, Hirata, Tomoko, Imai, Yuuki, Inoue, Kazunori, Kawasaki, Hiroshi, Kimura, Toshihiro, Kinoshita, Tomofumi, Kubo, Ken-Ichiro, Kunii, Yasuto, Lopez-Redondo, Fernando, Manabe, Ri-Ichiroh, Miyai, Tomohiro, Morimoto, Satoru, Nagaoka, Atsuko, Nakajima, Jun, Noma, Shohei, Okazaki, Yasushi, Ozaki, Kokoro, Saeki, Noritaka, Sakai, Hiroshi, Seyama, Kuniaki, Shibayama, Youtaro, Sujino, Tomohisa, Tagami, Michihira, Takahashi, Hayato, Masaki Takao, Takeshita, Masaru, Takiuchi, Tsuyoshi, Terao, Chikashi, Yip, Chi Wai, Yoshinaga, Satoshi, Okano, Hideyuki, Yamamoto, Kazuhiko, Takeya Kasukawa, Ando, Yoshinari, Carninci, Piero, Shin, Jay W, Chung-Chau, Hon
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 14.11.2023
• Subjects: Enhancers; Gene mapping; Gene regulation; Genetic diversity; Genomes; Heritability; Promoters; Regulatory sequences

Transcribed cis-regulatory elements (tCREs), such as promoters and enhancers, are fundamental to modulate gene expression and define cell identity. The detailed mapping of tCREs at single-cell resolution is essential for understanding the regulatory mechanisms that govern cellular functions. Prior t...