Spike-by-Spike Frequency Analysis of Amperometry Traces Provides Statistical Validation of Observations in the Time Domain

• Published in: arXiv.org
• Main Authors: Krishnan, Jeyashree, Lian, Zeyu, Oomen, Pieter E, He, Xiulan, Majdi, Soodabeh, Schuppert, Andreas, Ewing, Andrew
• Format: Paper
• Language: English
• Published: Ithaca Cornell University Library, arXiv.org 06.02.2023
• Subjects: Electrical measurement; Fast Fourier transformations; Fourier transforms; Frequency analysis; Frequency domain analysis; Open source software; Signal processing; Time domain analysis

Amperometry is a commonly used electrochemical method for studying the process of exocytosis in real-time. Given the high precision of recording that amperometry procedures offer, the volume of data generated can span over several hundreds of megabytes to a few gigabytes and therefore necessitates s...