Influence of silicon nanocone on cell membrane self-sealing capabilities for targeted drug delivery -- computer simulation study

• Published in: arXiv.org
• Main Authors: Raczyński, Przemysław, Górny, Krzysztof, Marciniak, Beata, Bełdowski, Piotr, Pöschel, Thorsten, Dendzik, Zbigniew
• Format: Paper
• Language: English
• Published: Ithaca Cornell University Library, arXiv.org 01.12.2022
• Subjects: Biocompatibility; Biomedical materials; Cell membranes; Chemotherapy; Computer simulation; Drug withdrawal; Hydrophobicity; Indentation; Lipids; Molecular dynamics; Nanomaterials; Phospholipids; Sealing

Efficient and non-invasive techniques of cargo delivery to biological cells are the focus of biomedical research because of their great potential importance for targeted drug therapy. Therefore, much effort is being made to study the characteristics of using nano-based biocompatible materials as sys...