When the Drug Becomes Toxic!: Lyell Syndrome in a Moroccan Context

• Published in: Drug safety Vol. 45; no. 10; p. 1277
• Main Authors: Imane, Z, Ouardi, A, Ababou, K, Gharbi, A E, Bencheikh, R S, Bousliman, Y, Tadlaoui, Y
• Format: Journal Article
• Language: English
• Published: Auckland Springer Nature B.V 01.10.2022
• Subjects: Amoxicillin; Analgesics; Antibiotics; Drugs; Genetic factors; Immunology; Lesions; Medical treatment; Paracetamol; Patients; Pharmacology; Pharmacovigilance; Pharynx; Phenylephrine; Public awareness; Resuscitation; Sepsis; Side effects; Skin diseases; Sulfamethoxazole; Toxic epidermal necrolysis; Trimethoprim

Introduction: Toxic epidermal necrolysis (NET) or Lyell's syndrome is a rare, unpredictable, and potentially fatal bullous toxiderma. The disease requires early management in an intensive care unit, at best in a burn resuscitation unit. Objective: To describe the clinical, paraclinical, therape...