Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1

• Published in: bioRxiv
• Main Authors: A King Cada, Mark Remec Pavlin, Castillo, Juan P, Tong, Alexander B, Larsen, Kevin P, Ren, Xuefeng, Yokom, Adam L, Feng-Ching, Tsai, Shiah, Jamie, Bassereau, Patricia, Bustamante, Carlos J, Hurley, James H
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 09.02.2022
• Subjects: Adenosine triphosphatase; Cytosol; Friction; HIV; Human immunodeficiency virus; Nanotubes

The endosomal sorting complexes required for transport (ESCRT) system is an ancient and ubiquitous membrane scission machinery that catalyzes the budding and scission of membranes. ESCRT-mediated scission events, exemplified by those involved in the budding of HIV-1, are usually directed away from t...