The medaka alg2 mutant is a model for hypo-N-glycosylation-associated retinitis pigmentosa
Patients suffering from Congenital Disorders of Glycosylation (CDG) carry mutations in components of the evolutionarily highly conserved protein-glycosylation-machinery. Employing targeted genome editing, we modeled alleles in medaka fish based on a mutation described in an ALG2-index patient. The m...
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Published in | bioRxiv |
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Main Authors | , , , , , , , , , |
Format | Paper |
Language | English |
Published |
Cold Spring Harbor
Cold Spring Harbor Laboratory Press
24.08.2020
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Subjects | |
Online Access | Get full text |
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