Clinical significance of serum CER, HA and FT3 in diagnosis of liver fibrosis in chronic hepatitis B patients
Objective To investigate the clinical significance of serum ceruloplasmin (CER), hyaluronic acid (HA) and free thyroxine 3 (FT3) in detecting liver fibrosis in patients with chronic hepatitis B (CHB). Methods One hundred and thirtysix cases of CHB patients, 44 cases of post-CHB cirrhosis patients, 2...
Saved in:
Published in | Jie fang jun yi xue za zhi Vol. 45; no. 6; p. 646 |
---|---|
Main Authors | , , , , , , , , , , , , , |
Format | Journal Article |
Language | Chinese |
Published |
Beijing
People's Military Medical Press
01.01.2020
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Objective To investigate the clinical significance of serum ceruloplasmin (CER), hyaluronic acid (HA) and free thyroxine 3 (FT3) in detecting liver fibrosis in patients with chronic hepatitis B (CHB). Methods One hundred and thirtysix cases of CHB patients, 44 cases of post-CHB cirrhosis patients, 20 cases with HBsAg-positive hepatocellular carcinoma (HCC), and 50 healthy controls were randomly selected from July 2014 to January 2018. Serum CER was detected by immune scattering turbidimetry, and direct chemiluminescence method was used for the detection of HA and FT3, one-way ANOVA analysis or rank sum test was used to compare the levels of serum CER, HA, FT3 and other related indexes between each group and the control group. Analysis of the correlation between CER, HA, FT3 and diagnosis model of liver fibrosis was performed and its results were analyzed using the receiver operating characteristic (ROC) curves. Results (1) The level of serum CER in severe CHB and decompensated liver cirrhosis group was signif |
---|---|
ISSN: | 0577-7402 |
DOI: | 10.11855/j.issn.0577-7402.2020.06.12 |