Thiol-oxidant monochioramine mobilizes intracellular Ca^sup 2+^ in parietal cells of rabbit gastric glands

• Published in: American Journal of Physiology: Cell Physiology Vol. 293; no. 5; p. C1687
• Main Authors: Walsh, Breda M, Naik, Haley B, Dubach, J Matthew, Beshire, Melissa, Wieland, Aaron M, Soybel, David I
• Format: Journal Article
• Language: English
• Published: Bethesda American Physiological Society 01.11.2007
• Subjects: Bacteria; Calcium; Cells; Oxidation; Proteins; Rabbits

In Helicobacter pylori-induced gastritis, oxidants are generated through the interactions of bacteria in the lumen, activated granulocytes, and cells of the gastric mucosa. In this study we explored the ability of one such class of oxidants, represented by monochloramine (...l), to serve as agonists...