Dyslipidemia of chronic renal failure: the nature, mechanisms, and potential consequences

• Published in: American journal of physiology. Renal physiology Vol. 59; no. 2; p. F262
• Main Author: Vaziri, N D
• Format: Journal Article
• Language: English
• Published: Bethesda American Physiological Society 01.02.2006
• Subjects: Cardiovascular disease; Cholesterol; Kidney diseases; Lipids; Metabolism

Chronic renal failure (CRF) results in profound lipid disorders, which stem largely from dysregulation of high-density lipoprotein (HDL) and triglyceride-rich lipoprotein metabolism. Specifically, maturation of HDL is impaired and its composition is altered in CRF. In addition, clearance of triglyce...