In vivo reactive oxygen species production induced by ischemia in muscle arterioles of mice: involvement of xanthine oxidase and mitochondria

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 294; no. 2; p. H21
• Main Authors: Baudry, Nathalie, Laemmel, Elisabeth, Vicaut, Eric
• Format: Journal Article
• Language: English
• Published: Bethesda American Physiological Society 01.02.2008
• Subjects: Anemia; Cells; Leukocytes; Mitochondrial DNA; Oxidation; Rodents

Reactive oxygen species (ROS) participate in tissue injury after ischemia-reperfusion. Their implication in leukocyte adherence and increase in permeability at the venular side of the microcirculation have been reported, but very little is known about ROS production in arterioles. The objective of t...