Disposition kinetics of [alpha]-tocopherol in apolipoprotein B knockout mice

• Published in: Pharmaceutical research Vol. 20; no. 3; p. 368
• Main Authors: Yokogawa, Koichi, Shima, Yuichiro, Hashimoto, Tomoka, Hiyajyo, Makoto
• Format: Journal Article
• Language: English
• Published: New York Springer Nature B.V 01.03.2003

We examined the effects of apolipoprotein B (apoB) on the disposition kinetics of alpha-tocopherol by using apoB knockout mice. The concentrations of alpha-tocopherol in plasma and tissues were measured by gas chromatography-mass spectrometry. In apob (-/-) mice, the endogenous levels of alpha-tocop...