NF-[kappa]B and the regulation of hematopoiesis

This review will focus on the role of nuclear factor kappaB (NF-kappaB) signaling in hematopoietic differentiation. We will also discuss several hematopoietic pathologies associated with deregulation of NF-kappaB and their potential therapies.

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Bibliographic Details
Published inCell death and differentiation Vol. 13; no. 5; p. 785
Main Authors Bottero, V, Withoff, S, Verma, I M
Format Journal Article
LanguageEnglish
Published Rome Nature Publishing Group 01.05.2006
Subjects
Cell death
Dendritic cells
Granulocytes
Kinases
Lymphocytes
Phosphorylation
Proteins
Tumor necrosis factor-TNF
La Jolla California
United States > US
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Summary:This review will focus on the role of nuclear factor kappaB (NF-kappaB) signaling in hematopoietic differentiation. We will also discuss several hematopoietic pathologies associated with deregulation of NF-kappaB and their potential therapies.
ISSN:1350-9047
1476-5403
DOI:10.1038/sj.cdd.4401888