Systematic, RNA-Interference-Mediated Identification of mus-101 Modifier Genes in Caenorhabditis elegans

• Published in: Genetics (Austin) Vol. 169; no. 4; p. 1451
• Main Authors: Holway, Antonia H, Hung, Crystal, Michael, W Matthew
• Format: Journal Article
• Language: English
• Published: Bethesda Genetics Society of America 01.04.2005
• Subjects: Chromosomes; DNA damage; Genes; Genetics

The Mus101 family of chromosomal proteins, identified initially in Drosophila, is widely conserved and has been shown to function in a variety of DNA metabolic processes. Such functions include DNA replication, DNA damage repair, postreplication repair, damage checkpoint activation, chromosome stabi...