New role of alpha-2-macroglobulin into the shedding of microvesicles

• Published in: Journal of extracellular vesicles Vol. 7; p. 218
• Main Authors: Laberge, Alexandra, Ayoub, Akram, Arif, Syrine, Larochelle, Sebastien, Garnier, Alain, Moulin, Veronique J
• Format: Journal Article
• Language: English
• Published: Abingdon John Wiley & Sons, Inc 01.01.2018
• Subjects: Angiogenesis; Extracellular matrix; Mass spectroscopy; Morphogenesis; Receptor density; Wound healing; α2-Macroglobulin

Background: Cells release membranous structures known as microvesicles (MVs) that play an important role in tissue morphogenesis and wound healing. Myofibroblasts are cells present in healing tissue that produce new extracellular matrix, stimulate angiogenesis and contract wound edges. They have bee...