Multiple candidate gene analysis identifies [alpha]-synuclein as a susceptibility gene for sporadic Parkinson's disease

• Published in: Human molecular genetics Vol. 15; no. 7; p. 1151
• Main Authors: Mizuta, Ikuko, Satake, Wataru, Nakabayashi, Yuko, Ito, Chiyomi, Suzuki, Satoko, Momose, Yoshio, Nagai, Yoshitaka, Oka, Akira, Inoko, Hidetoshi, Fukae, Jiro, Saito, Yuko, Sawabe, Motoji, Murayama, Shigeo, Yamamoto, Mitsutoshi, Hattori, Nobutaka, Murata, Miho
• Format: Journal Article
• Language: English
• Published: Oxford Oxford Publishing Limited (England) 01.04.2006

Parkinson's disease (PD), one of the most common human neurodegenerative diseases, is characterized by the loss of dopaminergic neurons in the substantia nigra of the midbrain. PD is a complex disorder with multiple genetic and environmental factors influencing disease risk. To identify suscept...