Prostaglandin E2 protects lower airways against bronchoconstriction

• Published in: American journal of physiology. Lung cellular and molecular physiology Vol. 34; no. 1; p. L105
• Main Authors: Hartney, John M, Coggins, Kenneth G, Tilley, Stephen L, Jania, Leigh A
• Format: Journal Article
• Language: English
• Published: Bethesda American Physiological Society 01.01.2006
• Subjects: Genetics; Lungs; Respiratory system; Rodents

Prostaglandin E2 (PGE2), similar to {beta}-adrenergic receptor agonists, can protect airways from bronchoconstriction and resulting increase in airway resistance induced by a number of agents, including cholinergic receptor agonists and antigen. We examined the impact of sustained alterations in PGE...