Experimental Physiology Mifepristone (RU38486) influences the core temperature response of term pregnant rats to intraperitoneal lipopolysaccharide

• Published in: Experimental physiology Vol. 91; no. 4; p. 741
• Main Authors: Moore, Sherry L, Fewell, James E
• Format: Journal Article
• Language: English
• Published: Oxford John Wiley & Sons, Inc 01.07.2006

Pregnancy alters the cytokine, prostanoid and core temperature responses of rats to infectious stimuli at a time when blood levels of the endogenous glucocorticoid corticosterone are elevated. Given that glucocorticoids attenuate bacterial pyrogen-induced fever in rats, the present experiments were...