DNA methylation and hydroxymethylation in early rabbit embryo: Consequence of in vitro culture

• Published in: Journal of animal science Vol. 94; pp. 37 - 38
• Main Authors: Bedhane, M N, Salvaing, J
• Format: Journal Article
• Language: English
• Published: Champaign Oxford University Press 01.09.2016
• Subjects: Activation; Cell culture; CpG islands; Culture media; Demethylation; Deoxyribonucleic acid; Developmental stages; DNA; DNA damage; DNA methylation; Embryogenesis; Embryonic growth stage; Embryos; Epigenetics; Genomes; Immunofluorescence; Metabolism; Nuclei; Oxidation; Pluripotency; Pregnancy; Proteins; Ribonucleic acid; RNA; Transcription

During the first developmental stages, the embryo's genome is transcriptionally silent and developmental changes are under control of maternally inherited factors (RNA and proteins). Embryonic genome activation (EGA) takes place at later stages (8-16 cell stage in rabbit) and involves epigeneti...