Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-[beta] burden in several amyloid transgenic mouse models - Latta-Mahieu, Martine; Elmer, Bradford; Bretteville, Alexis; Wang, Yaming; Lopez-Grancha, Mati; Goniot, Philippe; Moindrot, Nicolas; Ferrari, Paul; Blanc, Véronique; Schussler, Nathalie; Brault, Emmanuel; Roudieres, Valérie; et al. (Glia, 2018)
Keywords: Activation; Alzheimer's disease; Antibodies; Brain; Cell death; Immune checkpoint inhibitors; Immune system; Immunological tolerance; Infiltration; Macrophages; Medicine; Monocytes; Pathogenesis; Pathology; PD-1 protein; Therapeutic applications