Mineral trioxide aggregate enhances the osteogenic capacity of periodontal ligament stem cells via NF-[kappa]B and MAPK signaling pathways

• Published in: Journal of cellular physiology Vol. 233; no. 3; p. 2386
• Main Authors: Wang, Yanqiu, Zhou, Yixiang, Jin, Lin, Pang, Xiyao, Lu, Yadie, Wang, Zilu, Yu, Yan, Yu, Jinhua
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.03.2018
• Subjects: Alizarin; Alkaline phosphatase; Assaying; Biocompatibility; Cbfa-1 protein; Cell proliferation; Cholecystokinin; Conditioning; Cytoplasm; Differentiation; Immunofluorescence; Ligaments; MAP kinase; NF-κB protein; Nuclei; Periodontal ligament; Polymerase chain reaction; Proteins; Signaling; Stem cells; Transcription factors

Mineral trioxide aggregate (MTA), as a bioactive material, has a widespread application in clinical practice. To date, the effects of MTA on the proliferation and differentiation of human periodontal ligament stem cells (hPDLSCs) remain unclear. hPDLSCs were isolated from human periodontal ligament...