C80-B MULTI-MODALITY ASSESSMENT OF COPD, ASTHMA, AND ASTHMA-COPD OVERLAP SYNDROME: Excessive Expiratory Muscle Recruitment Impairs Central Hemodynamic Responses To Exercise In Patients With COPD

Rationale: Expiratory (largely abdominal) muscle recruitment during exercise is not only poorly efficient in increasing expiratory flow rates and reducing end-expiratory lung volumes[i] but may also have negative cardio-circulatory consequences.[ii] Our objective was to compare the central hemodynam...

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Bibliographic Details
Published inAmerican journal of respiratory and critical care medicine Vol. 195
Main Authors Berton, D C, Frohlich, L, Balzan, F M, Plachi, F, Gass, R, Merola, P K, Stein, R, Sanches, P R, Knorst, M M, Neder, J
Format Journal Article
LanguageEnglish
Published New York American Thoracic Society 01.01.2017
Subjects
Abdomen
Asthma
Chronic obstructive pulmonary disease
Exercise
Hemodynamics
Recruitment
United States > US
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Summary:Rationale: Expiratory (largely abdominal) muscle recruitment during exercise is not only poorly efficient in increasing expiratory flow rates and reducing end-expiratory lung volumes[i] but may also have negative cardio-circulatory consequences.[ii] Our objective was to compare the central hemodynamic responses to exercise in COPD patients with and without excessive abdominal muscles recruitment. [...]abdominal recruiters showed a flattened increment in stroke volume index and cardiac index during exercise compared to non-recruiters (Figure). [...]abdominal recruiters presented with lower end diastolic volume (left ventricle pre load) and lesser decrement in systemic vascular resistance index (left ventricle after load) compared to non-recruiters (Figure).
ISSN:1073-449X
1535-4970