Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-[kappa]B, Caspase-1/11, ASC, NOX, and NOS Isoforms
The nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3), an intracellular signaling molecule that senses many environmental- and pathogen/host-derived factors, has been implicated in the pathogenesis of several diseases associated with inflammation. It has been suggested that NLRP3 i...
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Published in | Inflammation Vol. 40; no. 2; p. 366 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer Nature B.V
01.04.2017
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Online Access | Get full text |
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