A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/[beta]-catenin Signaling in Humans and Mice

• Published in: Bone research Vol. 1; p. 27
• Main Authors: Maupin, Kevin A, Droscha, Casey J, Williams, Bart O
• Format: Journal Article
• Language: English
• Published: London Springer Nature B.V 01.03.2013

The Wnt signaling pathway plays key roles in differentiation and development and alterations in this signaling pathway are causally associated with numerous human diseases. While several laboratories were examining roles for Wnt signaling in skeletal development during the 1990s, interest in the pat...