PPAR[gamma] population shift produces disease-related changes in molecular networks associated with metabolic syndrome

• Published in: Cell death & disease Vol. 2; p. e192
• Main Authors: Jurkowski, W, Roomp, K, Crespo, I, Schneider, J G, Del Sol, A
• Format: Journal Article
• Language: English
• Published: London Springer Nature B.V 01.08.2011

Peroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of adipocyte differentiation and has an important role in metabolic syndrome. Phosphorylation of the receptor's ligand-binding domain at serine 273 has been shown to change the expression of a large number of genes impl...