Manganese-Catalyzed Oxidative Azidation of Cyclobutanols: Regiospecific Synthesis of Alkyl Azides by CC Bond Cleavage

• Published in: Angewandte Chemie International Edition Vol. 54; no. 43; p. 12692
• Main Authors: Ren, Rongguo, Zhao, Huijun, Huan, Leitao, Zhu, Chen
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 19.10.2015
• Edition: International ed. in English

A novel, manganese-catalyzed oxidative azidation of cyclobutanols is described. A wide range of primary, secondary, and tertiary alkyl azides were generated in synthetically useful yields and exclusive regioselectivity. Aside from linear alkyl azides, otherwise elusive medium-sized cyclic azides wer...