Expression and function of the epithelial sodium channel [delta]-subunit in human respiratory epithelial cells in vitro

• Published in: Pflügers Archiv Vol. 467; no. 11; p. 2257
• Main Authors: Schwagerus, Elena, Sladek, Svenja, Buckley, Stephen T, Armas-capote, Natalia, de la Rosa, Diego Alvarez, Harvey, Brian J, Fischer, Horst, Illek, Beate, Huwer, Hanno, Schneider-daum, Nicole, Lehr, Claus-michael, Ehrhardt, Carsten
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer Nature B.V 01.11.2015

Using human airway epithelial cell lines (i.e. NCI-H441 and Calu-3) as well as human alveolar epithelial type I-like (ATI) cells in primary culture, we studied the contribution of the epithelial sodium channel δ-subunit (δ-ENaC) to transepithelial sodium transport in human lung in vitro. Endogenous...