Hydroxypropyl-[beta]-cyclodextrin-mediated alterations in cell permeability, lipid and protein profiles of steroid-transforming Arthrobacter simplex

• Published in: Applied microbiology and biotechnology Vol. 99; no. 1; p. 387
• Main Authors: Shen, Yanbing, Liang, Jingting, Li, Huanan, Wang, Min
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer Nature B.V 01.01.2015
• Subjects: Biocatalysts; Biotechnology; Biotransformation; Dehydrogenases; Fatty acids; Investigations; Lipids; Microorganisms; Microscopy; Permeability; Phase transitions; Protein synthesis; Proteins; Steroids; Studies; China

Hydroxypropyl-cyclodextrin (HP-CD) enhances steroid 1-dehydrogenation biotransformation by Arthrobacter simplex. In this work, HP-CD-induced improvement of A. simplex CPCC 140451 cell envelope permeability which had positive effects on the steroid bioconversion was confirmed by a comparative investi...