Variantes alélicas del gen codificante del receptor de melanocortina 4 (MC4R) y su impacto en la expresión del fenotipo obeso/Melanocortin-4 receptor (MC4R) gene allelic variants and its impact on obese phenotype expression

• Published in: Revista latinoamericana de hipertensión Vol. 9; no. 1; p. 1
• Main Authors: Arráiz, Nailet, Rojas, Joselyn, Prieto, Carem, Mujica, Endrina, Amell, Anilsa, Sánchez, María Patricia, Urdaneta, Baldimiro, Marcucci, Rafael, Camacho, María Carolina, Levy, Alegría, González, Robys, Martínez, María Sofía, Chacín, Maricarmen, Bermúdez, Valmore
• Format: Journal Article
• Language: Spanish
• Published: Caracas Sociedad Latinoamericana de Hipertension 01.01.2014
• Subjects: Body mass index; Gene loci; Obesity; Proteins

Obesity is a public health problem worldwide, due to its association with other morbidities such as diabetes, hypertension and cardiovascular disease. It is estimated that approximately 65% -80% of the phenotypic variation in obesity is due to genetic variation between individuals. MC4R is one of th...